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Risk Factors
Summary of Risk Factors
The table below summarizes the risk factors for developing cutaneous melanoma.
| New mole, preexisting mole that has changed or is changing |
High (10-400)** |
| Dysplastic nevi, prior melanoma, & familial melanoma |
500 |
| Dysplastic nevi, no prior melanoma & familial melanoma |
148 |
| Dysplastic nevi, no personal or family history of melanoma |
7-27 |
| Congenital nevus |
2-21 |
| 20 nevi at least 2 mm diameter (if 50 nevi or more) |
7-14 (then 54) |
| 5 nevi _ 7 mm diameter (if _ 8 nevi) |
6 (then 17) |
| 5 moles at least 5 mm diameter (if 12 nevi or more) |
10 (then 41) |
| Lentigo maligna |
10 |
| Caucasian (vs African American) |
20 |
| Prior cutaneous melanoma |
9 |
| Cutaneous melanoma in first degree blood relative |
8 |
| Immunosuppression |
4 |
| Sun-induced freckles by history |
3 |
| Sun sensitivity, relative inability to tan |
3 |
| Red hair, blond hair, or green or blue eyes |
1-2 |
| Excessive sun exposure |
controversial |
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*Degree of increased risk for people with the risk factor, compared to people without the risk factor.
Data derived from case-control and prospective studies. Relative risk of 1.0 indicates no increased risk.
**Risk estimated to be increased 10-fold to 400-fold, depending on the prevalence of new or changing mole
in the general population.
Information provided by A. Rhodes, as modified from Rhodes et al, in 5th edition of Fitzpatrick's Dermatology
in General Medicine, p 1026, Table 90-1.
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